San Francisco 17:19:19
Cologne 02:19:19
Cape Town 03:19:19
Dubai 05:19:19
I would cure all diseases if I only could produce fever.
Parmenides (Greek philosopher, 510 BC.)
Introduction
During the evolution of vertebrae, from
fish to amphibians, from birds to mammals, one can observe the development of
a "warmth organism", or "warmth organisation", which becomes gradually
independent from temperatures of the surroundings. In humans, the regulation
of body temperature is most developed. Especially in man, the blood flow
through the skin is more developed than in any other mammalian organism, and
serves the regulation of body temperature through vasoconstriction and
vasodilatation, and through production and perfusion of sweat by the sweat
glands. Missing a thick layer of hair (fur), the human body is very open to
changes of temperature in the environment. Therefore, in order to maintain a
stable core temperature, the human organism must be able to adjust to changes
in temperature quickly, easily and effectively. Isothermia and augmentation
of adaptation to changes in temperature are evolutionarily connected with the
development of the circadian rhythm of the core temperature. In addition, the
exchange of warmth between core temperature and the temperature of the
environment, or periphery, or skin, is another example of augmentation of
maintaining a stabile core temperature.
Newborns have not yet developed a functioning circadian rhythm. Only after
about 4 weeks, day rhythms start to occur. In adults, the circadian rhythm
forms a sinus curve with maxima and minima around 18.00 and 6.00. o´clock.
The amplitude is usually around 0,6 degrees C.
In cancer patients, and patients with other chronic diseases, like chronic
viral infections and degenerative diseases, not only the circadian rhythm of
the core temperature changes significantly and becomes chaotic, but also the
amplitude becomes flat and the delicate interaction between core- and
peripheral temperatures is inhibited (1). Therefore, in the Cologne Model,
patients will undergo therapeutic interventions to improve both his circadian
rhythm and its amplitude, and the maintenance of a stabile core
temperature.
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